DBCO-PEG4-NHS Ester

貨號(hào)
規(guī)格
價(jià)格
品牌
貨期
A134-2
4*2 mg
2580.0
ClickChemistryTools
現(xiàn)詢
A134-10
10 mg
1900.0
ClickChemistryTools
現(xiàn)詢
A134-25
25 mg
3900.0
ClickChemistryTools
現(xiàn)詢
A134-100
100 mg
9900.0
ClickChemistryTools
現(xiàn)詢
A134-500
500 mg
33900.0
ClickChemistryTools
現(xiàn)詢

DBCO-PEG4-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary azide-containing molecules.

分子量
649.68
分子式
C34H39N3O10
CAS
1427004-19-0
溶(解)度
DMF, DMSO, DCM, THF, Chloroform
純度
>95% (HPLC)
外觀
Yellow to slightly orange oil
儲(chǔ)存環(huán)境
-20°C. Desiccate
運(yùn)輸條件
Ambient temperature

1.Wang X., et al. (2021). Equipping Natural Killer Cells with Cetuximab through Metabolic Glycoengineering and Bioorthogonal Reaction for Targeted Treatment of KRAS Mutant Colorectal Cancer. ACS Chem. Biol., 16 (4), 724-730. [PubMed]

2.Ahn, S.H., et al. (2020). Site-Specific 89Zr- and 111In-Radiolabeling and In Vivo Evaluation of Glycan-free Antibodies by Azide–Alkyne Cycloaddition with a Non-natural Amino Acid. Bioconjugate Chem., 31(4), 1177-87. [PubMed]

3.Pack, J., et al. (2020). Site-Specific Antibody Conjugation Strategy to Functionalize Virus-Based Nanoparticles. Bioconjugate Chem., 31(5), 1408-16. [PubMed]

4.Huynh, V., et al. (2018). Competitive Affinity Release for Long-Term Delivery of Antibodies from Hydrogels. Bioconjugate Chem., 57(13), 3406-10. [PubMed]

5.Nedrow-Byerst, J.R., et al. (2013). PSMA-targeted SPECT agents: mode of binding effect on in vitro performance. Prostate., 73(4), 355-62. [PubMed]


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